Function of oval cells in hepatocellular carcinoma in rats

Table 1 Number of cancerous nodes and cancer nodes area in rat liver (mean ± SD, n = 8)

t/wk	Cases of hepatic cancer		Number of cancerous		Area of cancer nodes (mm2)
	A	B	A	B	A	B
2-4	0	0	0	0	0	0
6-8	0	0	0	0	0	0
10-12	2	0	4	0	9.5 ± 8.2	0
14-16	6	2	15	5	10.7 ± 8.7	5.8 ± 4.5a
18-20	8	4	17	9	11.4 ± 8.9	8.5 ± 7.6
22-24	8	4	16	10	11.2 ± 9.3	8.6 ± 7.3

^aP < 0.05 vs group A; A: cancer- induction group; B: intervention group.

Table 2 PCNA positive index and c-myc relative gray value in liver (mean ± SD)

t/wk	Cancer induction (n = 8)			Intervention (n = 8)		Control (n = 4) RGV
	PCNA (%)	RGV	PCNA (%)	RGV	PCNA (%)
2-4	14.1 ± 7.5a	1.3 ± 1.0	7.6 ± 3.3	1.2 ± 0.6	3.0 ± 1.2	1.0 ± 0.3
6-8	48.2 ± 15.5b	2.0 ± 07	24.3 ± 7.4a	1.5 ± 0.7	2.9 ± 1.5	1.1 ± 0.4
10-12	23.7 ± 9.6a	3.6 ± 1.2a	35.1 ± 6.5b	2.2 ± 0.9	3.3 ± 0.9	1.1 ± 0.5
14-16	25.9 ± 5.1a	5.7 ± 1.4a	21.5 ± 4.2a	3.5 ± 1.0a	3.7 ± 2.1	1.3 ± 0.4
18-20	36.8 ± 6.3b	7.8 ± 1.4a	29.6 ± 7.6a	6.5 ± 1.1a	3.6 ± 1.3	1.3 ± 0.6
22-24	41.2 ± 8.2b	8.2 ± 2.2b	30.2 ± 8.7a	8.0 ± 1.3b	3.5 ± 2.2	1.3 ± 0.4

^aP < 0.05,

^bP < 0.01 vs group C; RGV: Relative gray value.