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©The Author(s) 2024.
World J Gastroenterol. Jul 28, 2024; 30(28): 3403-3417
Published online Jul 28, 2024. doi: 10.3748/wjg.v30.i28.3403
Published online Jul 28, 2024. doi: 10.3748/wjg.v30.i28.3403
Univariate analysis1 | Multivariate analysis1 | Univariate analysis2 | Multivariate analysis2 | |||||
HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | |
Sex (male) | 1.148 (0.588-2.243) | 0.686 | 1.168 (0.648-2.106) | 0.605 | ||||
Age (> 60) | 2.194 (1.115-4.317) | 0.023 | 2.875 (1.505-5.495) | < 0.001 | ||||
PLR (> 128.00) | 1.592 (0.818-3.100) | 0.171 | 1.313 (0.668-2.577) | 0.402 | ||||
NLR (> 1.45) | 1.629 (0.740-3.585) | 0.226 | 2.322 (1.106-4.874) | 0.007 | ||||
PNI (> 46.57) | 0.144 (0.071-0.295) | 0.023 | 0.233 (0.109-0.499) | < 0.001 | 0.130 (0.043-0.392) | < 0.001 | 0.365 (0.135-0.583) | 0.010 |
Size (cm) | ||||||||
≤ 1 | - | Ref. | - | Ref. | - | Ref. | ||
1-2 | 6.190 (2.591-14.790) | < 0.001 | 1.706 (0.538-5.413) | 0.364 | 4.960 (1.956-12.580) | 0.001 | ||
> 2 | 13.439 (5.563-32.468) | < 0.001 | 3.349 (1.314-8.533) | 0.011 | 10.240 (5.200-25.200) | < 0.001 | ||
Pathological type | ||||||||
NET | - | Ref. | - | Ref. | ||||
NEC | 31.177 (14.961-64.968) | < 0.001 | 15.121 (5.590-59.102) | < 0.001 | ||||
MANEC | 27.899 (6.399-121.627) | < 0.001 | 26.252 (6.203-85.32) | < 0.001 | ||||
Pathological grade | ||||||||
G1 | - | Ref. | - | Ref. | - | Ref. | - | Ref. |
G2 | 6.380 (2.582-15.768) | 0.001 | 4.211 (1.603-11.059) | 0.004 | 8.680 (2.830-20.602) | < 0.001 | 2.937 (1.011-8.535) | 0.048 |
G3 | 48.175 (21.495-107.969) | < 0.001 | 30.681 (10.821-86.988) | < 0.001 | 25.362 (6.362-62.325) | < 0.001 | 7.126 (2.685-18.913) | < 0.001 |
T stage | ||||||||
T1 | - | Ref. | - | Ref. | - | Ref. | ||
T2 | 3.234 (1.169-8.945) | 0.024 | 13.370 (3.794-47.086) | < 0.001 | 2.136 (1.236-5.362) | 0.025 | ||
T3 | 17.473 (7.846-38.915) | < 0.001 | 12.630 (2.635-18.354) | < 0.001 | 6.653 (2.368-15.362) | 0.001 | ||
T4 | 23.081 (8.328-63.964) | < 0.001 | 26.368 (5.364-53.258) | < 0.001 | 8.365 (3.325-13.325) | < 0.001 | ||
Lymph node metastasis (yes) | 11.387 (5.786-22.409) | < 0.001 | 12.440 (4.172-37.112) | < 0.001 | ||||
TNM stage | ||||||||
I | - | Ref. | - | Ref. | ||||
II | 3.280 (1.188-9.056) | 0.022 | 6.839 (1.692-27.650) | 0.006 | ||||
III | 14.524 (7.080-29.797) | < 0.001 | 17.792 (5.982-52.932) | < 0.001 | ||||
Lymph vascular invasion (yes) | 5.753 (2.013-16.447) | 0.001 | 5.899 (1.213-28.703) | < 0.001 | ||||
CgA (positive) | 1.992 (1.012-3.919) | 0.046 | 1.188 (0.608-2.322) | 0.512 | ||||
Syn (positive) | 1.161 (0.541-2.492) | 0.702 | 0.960 (0.483-1.908) | 0.919 | ||||
Adjuvant therapy (yes) | 10.775 (5.161-22.499) | < 0.001 | 13.110 (3.737-45.962) | < 0.001 |
- Citation: Zeng XY, Zhong M, Lin GL, Li CG, Jiang WZ, Zhang W, Xia LJ, Di MJ, Wu HX, Liao XF, Sun YM, Yu MH, Tao KX, Li Y, Zhang R, Zhang P. GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience. World J Gastroenterol 2024; 30(28): 3403-3417
- URL: https://www.wjgnet.com/1007-9327/full/v30/i28/3403.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i28.3403