Basic Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Dec 21, 2022; 28(47): 6752-6768
Published online Dec 21, 2022. doi: 10.3748/wjg.v28.i47.6752
Figure 1
Figure 1 Interleukin-34 is elevated in colitis and colitis-related cancers. A: Interleukin-34 (IL-34) relative mRNA expression in stomach, jejunum, ileum and colon in wild-type mice (C57BL/6J) (n = 6); B and C: The dynamic of IL-34 expression in dextran sodium sulfate (DSS)-induced colitis and azoxymethane-DSS-induced colorectal cancer in wild-type mice (n = 6 per group); representative IL-34 immunohistochemical staining for healthy control, acute colitis, chronic colitis and colorectal cancer mice (B); the percentage of IL-34-positive cells per high-power field were quantified in colonic tissue of four groups of mice (n = 6 per group) (C). AOM: Azoxymethane; CRC: Colorectal cancer; DSS: Dextran sodium sulfate; IL-34: Interleukin-34. Scale bars = 100 μm. Data depict the mean ± SD. aP < 0.05, bP < 0.01, cP < 0.005, dP < 0.001.