Case Control Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. Jun 28, 2021; 27(24): 3609-3629
Published online Jun 28, 2021. doi: 10.3748/wjg.v27.i24.3609
Figure 5
Figure 5 Mucosal immunohistochemistry in patients with ulcerative colitis and healthy controls. A and B: Takeda G protein-coupled receptor 5 (TGR5) immunoreactivity was mainly scattered in the epithelium in ulcerative colitis (UC) patients (scale bar = 20 μm); C and D: Vitamin D receptor (VDR) immunoreactivity was distributed in the epithelium and lamina propria in UC patients and healthy controls (Scale bar = 20 μm); E: The mean optical density of TGR5 in the colonic mucosa in UC patients was significantly higher than that in healthy controls (P = 0.0003); F: The mean optical density of VDR in the colonic mucosa decreased significantly in patients (P = 0.033). UC: Ulcerative colitis; TGR5: Takeda G protein-coupled receptor 5; VDR: Vitamin D receptor; MOD: Mean optical density.