Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis

Figure 3 High expression of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 was significantly associated with poorer progression-free survival and overall survival in patients with colorectal cancer. Cumulative progression-free survival and overall survival of colorectal cancer patients in different groups were compared. A and B: Doublecortin-like kinase 1 (DCLK1)^High and DCLK1^Low; C and D: Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5)^High and Lgr5^Low; E and F: DCLK1^High/Lgr5^High and others. DCLK1: Doublecortin-like kinase 1; Lgr5: Leucine-rich repeat-containing G-protein-coupled receptor 5; PFS: Progression-free survival; OS: Overall survival.