Identification of differentially expressed genes in ulcerative colitis and verification in a colitis mouse model by bioinformatics analyses

Table 3 Top three enriched terms in the respective categories of downregulated differentially expressed genes identified in ulcerative colitis (P < 0.05)

Category	Term	Count	Genes
BP	Transmembrane transport (GO: 0055085)	9	TRPM6, SLC23A1, SLC16A1, SLC25A34, SLC17A4, ABCB1, AQP7, SLC30A10, SLC26A2.
BP	Carboxylic acid transport (GO: 0046942)	5	SLC38A4, SLC23A1, SLC16A1, AQP8, SLC3A1.
BP	Organic acid transport (GO: 0015849)	5	SLC38A4, SLC23A1, SLC16A1, AQP8, SLC3A1.
CC	Cell fraction (GO: 0000267)	12	HSD3B2, SLC23A1, SLC16A1, AQP8, SLC17A4, CYP2B6, MEP1B, ABCB1, ANPEP, SLC3A1, SLC26A2, PCK1.
CC	Membrane fraction (GO: 0005624)	10	HSD3B2, SLC23A1, SLC16A1, AQP8, SLC17A4, CYP2B6, MEP1B, ABCB1, SLC3A1, SLC26A2.
CC	Insoluble fraction (GO: 0005626)	10	HSD3B2, SLC23A1, SLC16A1, AQP8, SLC17A4, CYP2B6, MEP1B, ABCB1, SLC3A1, SLC26A2.
MF	Symporter activity (GO: 0015293)	4	SLC38A4, SLC23A1, SLC16A1, SLC17A4.
MF	Xenobiotic-transporting ATPase activity (GO: 0008559)	2	ABCB1, ABCG2.
MF	Multidrug transporter activity (GO: 0015239)	2	ABCB1, ABCG2.

MF: Molecular function; CC: Cellular component; BP: Biological process.