Intestinal dysbiosis in pediatric Crohn's disease patients with IL10RA mutations

Table 3 Correlation of dysbiosis index with clinical variables

Variable	Combined, r1 (P value)	IL10RA, r (P value)	CD, r (P value)
wPCDAI	0.52 (0.002)	0.51 (0.040)	0.54 (0.027)
SES-CD	0.48 (0.005)	0.51 (0.044)	0.35 (0.174)
MINI index	0.26 (0.131)	0.32 (0.213)	0.17 (0.510)
CRP, mg/L	0.11 (0.532)	0.16 (0.526)	0.18 (0.493)
IL6, pg/mL	0.17 (0.346)	0.22 (0.417)	0.01 (0.961)
Hb, g/L	-0.54 (0.0009)	-0.56 (0.022)	-0.51 (0.037)
Disease duration (mo)	-0.35 (0.045)	-0.50 (0.043)	-0.40 (0.109)

¹Spearman's rank order correlation coefficient. wPCDAI: Weighted pediatric Crohn's disease activity index; SES-CD: Simple endoscopic score for Crohn's disease; MINI: Mucosal-inflammation non-invasive; CRP: C-reactive protein; IL6: Interleukin 6; Hb: Hemoglobin.