Copyright ©The Author(s) 2019.
World J Gastroenterol. Aug 7, 2019; 25(29): 3897-3919
Published online Aug 7, 2019. doi: 10.3748/wjg.v25.i29.3897
Table 1 Definitions of the grading of the recommendations
PreferredTreatment can be used in most patients and recommendation is based on optimal efficacy, favorable tolerability, toxicity profiles, treatment duration, and pill burden
AlternativeTreatment can be the one that is effective but with potential disadvantages/limitations in certain patient populations or with less supporting data as compared with the recommended regimens; in certain situations, an alternative regimen may be an optimal regimen for a specific patient population
Not recommendedTreatment is clearly inferior compared with the recommended or alternative regimens because of factors such as lower efficacy, unfavorable tolerability, toxicity, longer duration, and/or higher pill burden. Unless otherwise indicated, such regimens should not be administered in HCV-infected patients