Non-guided self-learning program for high-proficiency optical diagnosis of diminutive and small colorectal lesions: A single-endoscopist pilot study

Table 5 Comparison of the diagnostic performance measures and Preservation and Incorporation of Valuable Endoscopic Innovations criteria fulfillment between the two halves of the study

Parameter		1st half, n = 1651	2nd half, n = 1821
Sensitivity		96.1 (93.1-99.0)	97.6 (95.4-99.8)
Specificity		82.0 (76.1-87.9)	65.4 (58.5-72.3)
PPV		90.1 (85.5-94.7)	87.2 (82.3-92.0)
NPV		92.6 (88.6-96.6)	91.9 (87.9-95.9)
Accuracy		90.1 (85.6-94.7)	88.2 (87.9-95.9)
NPV rectosigmoid lesions		92.3 (87.3-96.6)	90.5 (86.2-94.8)
Surveillance interval agreement
	UE	100.0	93.3 (89.7-96.9)
	ESGE	100.0	95.1 (92.0-98.2)
	ASGE	100.0	93.3 (91.6-98.2)

Data are given as % (95%CI).

¹Only for diminutive lesions diagnosed with high-confidence.

ASGE: American Society of Gastrointestinal Endoscopy; ESGE: European Society of Gastrointestinal Endoscopy; EU: European Union; NPV: Negative predictive value; PIVI: Preservation and Incorporation of Valuable Endoscopic Innovations; PPV: Positive predictive value.