Copyright ©The Author(s) 2019.
World J Gastroenterol. Jan 7, 2019; 25(1): 42-58
Published online Jan 7, 2019. doi: 10.3748/wjg.v25.i1.42
Figure 6
Figure 6 Interaction between the PPARα signaling pathway and HCV core protein. HCV core protein can directly and indirectly activate PPARα, and PPARα activation increases liver triglyceride accumulation, leading to hepatic steatosis. See the text for more details. PPARα: Peroxisome proliferator-activated receptor α; ROS: Receptor tyrosine kinase c-ros oncogene 1; RXR: Retinoid X receptor; PPRE: Peroxisome proliferator hormone response elements.