Prognostic significance of computed tomography-detected extramural vascular invasion in colon cancer

Table 4 Univariate and multivariate analyses for disease-free survival of colon cancer

Variable	Group	Patient count	Univariate analysis			Multivariate analysis
			HR	95%CI	P value	HR	95%CI	P value
Gender	Female	93
	Male	101	1.164	0.652-2.078	0.606	1.288	0.714-2.326	0.403
Age (yr)	< 65	74
	≥ 65	120	1.105	0.612-1.997	0.742	1.618	0.838-3.122	0.154
Location	Right	106
	Left	88	0.820	0.458-1.468	0.509	0.849	0.464-1.553	0.597
ctEMVI	Negative	134
	Positive	60	3.593	1.868-6.911	< 0.0001	2.151	1.118-4.138	0.023
pT	≤ T2	25
	T3	35
	T4a	105
	T4b	29	N/A	N/A	< 0.0001	1.876	1.161-3.029	0.011
pN	N0	100
	N1	58
	N2	36	N/A	N/A	< 0.0001	2.031	1.391-2.966	0.000
D	Well/moderate	136
	Poor	58	1.453	0.767-2.751	0.217	1.006	0.527-1.920	0.985

ctEMVI: Computed tomography-detected extramural vascular invasion; pT: Pathological tumor status; pN: Pathological lymph node status; D: Differentiation.