Hepatocellular carcinoma in the elderly: Meta-analysis and systematic literature review

Table 2 Preoperative data of patients with hepatocellular carcinoma who underwent surgical resection

Author	Year	Country	Design	Age cut off	Young, n	Elderly, n	Sex: male/female (P = 0.6947)		Child Pugh A/B		Tumor size (cm)(P = 0.984)
							Y	E	Y	E	Y	E
Yau et al[27]	1999	China	Prospective	70	299	31	255/44	21/10	285/14	30/1	7.9	8.0
Wu et al[8]	1999	Taiwan	Retrospective	80	239	21	190/49	19/2	194/34	16/4	6.5	7.0
Hanazaki et al[8]	2001	Japan	Retrospective	70	283	103	222/61	71/32	226/56	76/27	NA	NA
Yeh et al[9]	2004	Taiwan	Prospective	70	398	34	310/88	27/7	152/199	12/18	6.7	5.5
Ferrero et al[10]	2005	Italy	Prospective	70	177	64	145/32	47/17	138/37	54/8	NA	NA
Kaibori et al[11]	2009	Japan	Retrospective	70	333	155	269/64	119/36	302/31	139/16	4.32	3.76
Oishi et al[4]	2009	Japan	Prospective	75	502	64	381/121	48/16	427/NA	59/NA	3.3	3.9
Huang et al[12]	2009	China	Retrospective	70	268	67	222/46	58/9	257/11	63/4	7.4	7.3
Mirici-Cappa et al[13]	2009	Italy	Retrospective	70	43	142	116/26	32/11	123/18	40/3	4.09	3.42
Tsujita et al[14]	2012	Japan	Prospective	80	385	23	253/132	15/8	264/121	18/5	3.2	3.5
Yamada et al[15]	2012	Japan	Prospective	80	267	11	205/62	6/5	245/22	9/2	4.8	5.2
Nishikawa et al[16]	2013	Japan	Prospective	75	206	92	161/45	61/31	198/8	90/2	4.8	4.6
Hirokawa et al[17]	2013	Japan	Retrospective	70	120	100	99/21	69/31	98/22	88/12	3.0	3.5
Ide et al[18]	2013	Japan	Retrospective	75	192	64	157/35	43/21	168/24	57/7	4.9	4.9
Taniai et al[19]	2013	Japan	Retrospective	75	353	63	271/82	39/24	265/84	56/7	NA	NA
Liu et al[20]	2014	Taiwan	Prospective	75	730	129	571/159	107/22	694/36	116/13	NA	NA
Kishida et al[21]	2015	Japan	Retrospective	75	82	22	66/16	20/2	NA	NA	3.0	3.5
Kim et al[22]	2015	South Korea	Retrospective	70	219	60	168/51	46/14	NA	NA	4.9	4.9

NA: Not available; E: Elderly; Y: Young.