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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 28, 2014; 20(44): 16620-16629
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16620
Table 1 Phenotype-Genotype correlations in familial adenomatous polyposis patients
AFAPAPC extreme ends (exons 3,4,5) and exon 9Spirio et al[5] 1993
Profuse polyposis (approximately 5000 polyps)Between codons 1250-1464Nagase et al[6] 1992
Severe polyposis and early CRC onsetDeletion in codon 1309Caspari et al[7] 1995
Desmoid tumorBetween codons 1444-1580Caspari et al[7] 1995
CHRPEBetween codons 463-1387Olschwang et al[8] 1993
Thyroid cancer5' to codon 1220Cetta et al[9] 2000
Duodenal adenomasBetween codons 976-1067Bertario et al[10] 2003
Rectal cancerCodons 1250 to 1464Bertario et al[11] 2000