Original Article
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 7, 2014; 20(37): 13521-13529
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13521
Figure 1
Figure 1 Effect of neonatal acetic acid treatment on 8-wk-old rat sensitivity to colorectal distension. A: Abdominal withdrawal reflex (AWR) responses to the graded pressures of colorectal distension (CRD) in saline-treated (n = 10) and acetic acid-treated (n = 10) rats. Acetic acid-treated rats show increased AWR scores compared with the saline rats. Values are expressed as mean ± SD; B: Representative electromyogram (EMG) traces recorded in control and acetic acid-treated rats in response to CRD; C: EMG responses to CRD in rats treated with saline and acetic acid at the neonatal stage. Similar to the AWR scores, acetic acid-treated rats exhibited exaggerated EMG activity responses to CRD at different pressures compared with the saline-treated rats. Neonatal rats vs control rats, aP < 0.05, bP≤ 0.01, error bars represent the mean ± SD.