Tumor necrosis factor-α mediates JNK activation response to intestinal ischemia-reperfusion injury

Figure 6 Tumor necrosis factor-α mediated c-Jun N-terminal kinase activation response to mucosal injury in ischemia-reperfusion-induced intestine. Equal quantities of protein were subjected to Western blotting analysis, and β-actin was used as the control for loading. The results were expressed as a ratio of densitometry units. A: Western blotting analysis; B: The ratio of p-c-Jun N-terminal kinase (JNK) and JNK; C: The ratio of p-c-Jun and c-Jun. Values are mean ± SE. Six rats were tested in each group. ^aP < 0.05 vs sham-operation(SO) rats pretreated with vehicle (SO + vehicle); ^cP < 0.05 vs ischemia-reperfusion (I/R) rats pretreated with vehicle (I/R + vehicle). PTX: Pentoxifylline; IFX: Infliximab.