Original Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 14, 2012; 18(26): 3389-3399
Published online Jul 14, 2012. doi: 10.3748/wjg.v18.i26.3389
Figure 7
Figure 7 Over expression of the three osteopontin splice variants promotes Huh-7 tumour growth in Balb/c nude mice. A: Growth of tumours in mice injected in the hind flanks with osteopontin (OPN)-A, -B, -C or control-expressing stable cell lines, with mean tumour volumes at the time of euthanasia expressed graphically in (B) aP < 0.05 OPN-A/Huh-7 vector only; C: Polymerase chain reaction analysis of a representative tumour from each of the 4 groups showing OPN mRNA expression in all tumours; D: OPN-a expressing tumours display increased levels of OPN protein. Control and OPN-A tumour sections were immunostained for OPN in conjunction with a rabbit isotype control. Bar represents 100 μm.