Guidelines For Basic Science
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 14, 2012; 18(22): 2745-2755
Published online Jun 14, 2012. doi: 10.3748/wjg.v18.i22.2745
Figure 4
Figure 4 MiRNA biogenesis and genes mutated in microsatellite instability+ gastrointestinal cancers. A consequence of perfect complementarity between miRNA and mRNA is mRNA cleavage and degradation. Imperfect alignment represses gene translation. ORF: Open reading frame; RISC: RNA-induced silencing complexes.