Original Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2011; 17(8): 976-986
Published online Feb 28, 2011. doi: 10.3748/wjg.v17.i8.976
Figure 6
Figure 6 Oral administration of cinnamon extract ameliorates experimental colitis. Mice were orally fed with PBS or cinnamon extract (CE) (50 μg/g per day) for 20 d, and intestinal colitis was induced by intrarectal injection of TNBS (50 μg/g in 50% ethanol). A: A change in body weight was monitored for 5 d; B: Gross intestinal changes were analyzed with a magnifying glass 3 d after colitis induction; C: After HE staining, histological analysis was performed by comparing colon sections of treatment groups; D: After induction of inflammatory bowel disease, cyclooxygenase (COX)-2 expression in mesenteric lymph nodes was compared by quantitative real-time PCR and immunoblotting; E: Expression levels of cytokines in mesenteric lymphocytes were measured by quantitative real-time PCR; F: Intracellular protein levels of interleukin (IL)-10 and tumor necrosis factor (TNF)-α were measured by flow cytometry. Error bars indicated SD. bP < 0.005, cP < 0.001. Data are representative of three independent experiments. IFN: Interferon.