Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2011; 17(18): 2288-2301
Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2288
Table 7 Effects of silybin on hepatic metabolism of glucose at doses of 25-100 μmol/L in hepatocytes[100-102]
DosesCellTargets
25-100 μmol/LHepatocytesInhibition of pyruvate kinase
Inhibition of glycolytic flux
Inhibition of glucose-6-phosphate hydrolysis
Inhibition of glucose-6-phosphatase