Silybin and the liver: From basic research to clinical practice

doi:10.3748/wjg.v17.i18.2288

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May 14, 2011 (publication date) through Dec 10, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 14, 2011; 17(18): 2288-2301
Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2288

Table 2 Pharmacokinetics of silybin after administration to 12 healthy volunteers as silymarin or silybin-phosphatidylcholine-vitamine E complex (RA)[43]

Product	Cmax (ng/mL)	Tmax(h)	AUC (ng/mL per hour)
RA granules (47 mg silybin)	213 ± 166	0.5	246 ± 114
RA capsules (47 mg silybin)	117 ± 93	1.0	161 ± 85
Silymarin gran (58 mg silybin)	18 ± 17	0.5	25 ± 18
Silymarin caps (80 mg silybin)	5 ± 7	1.0	11 ± 5

Citation: Loguercio C, Festi D. Silybin and the liver: From basic research to clinical practice. World J Gastroenterol 2011; 17(18): 2288-2301
URL: https://www.wjgnet.com/1007-9327/full/v17/i18/2288.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i18.2288