Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2011; 17(18): 2273-2282
Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2273
Table 1 Diagnostic tests, suggested etiology, and current treatment for the most frequent forms of liver cirrhosis in adult patients
Abnormal test(s)EtiologyTreatment
γGT (high), MCV (high)AlcoholAbstinence
HBsAg, HBV-DNA, HBc-IgM, HDV-RNA (positivity)HBV + Delta virus infectionInterferon α-2b, nucleoside (Lamivudine, Telbivudine, Entecavir) and nucleotide (Adefovir, Tenofovir) analogues
HCV-RNA (positivity)HCV infectionInterferon plus ribavirin
γGT (high), alkaline phosphatase (high), AMA (positivity)Primary biliary cirrhosisUrsodeoxycholate
ANA, ASMA, LKM (positivity)Autoimmune hepatitisPrednisone, azathioprine
Ferritin (high), transferring saturation index (> 45%), liver iron content (high), HFE gene mutation for hereditary hemochromatosis (C282Y, H63D)HemochromatosisPhlebotomy, deferoxamine
Ceruloplasmin (low), serum (low) and 24 h urine copper excretion (high)Wilson’s diseaseD-penicillamine, zinc
HDL-cholesterol (low), glucose (high), triglycerides (high)NAFLD/NASHLow caloric diet, exercise, drugs lowering insulin-resistance