Sunitinib for Taiwanese patients with gastrointestinal stromal tumor after imatinib treatment failure or intolerance

Table 4 Adverse events and selected laboratory abnormalities

Variable	Sunitinib (n = 23)
	Grade 1	Grade 2	Grade 3	Grade 4
Adverse event
Anorexia	5	1	0	0
Diarrhea	6	8	0	0
Constipation	1	2	0	0
Fatigue	2	2	0	0
Nausea	0	0	0	0
Mucositis/stomatitis	4	0	0	0
Vomiting	1	0	0	0
Hypertension	4	4	1	0
Hand-foot syndrome	1	2	6	0
Rash	1	4	0	0
Skin discoloration	5	0	0	0
Fever	2	0	1	0
Laboratory abnormalities
Leukopenia	4	6	1	0
Neutropenia	2	4	3	0
Febrile neutropenia	0	0	1	0
Anemia	8	6	4	0
Elevated creatinine	4	4	0	0
Thrombocytopenia	6	7	0	0
AST	7	1	0	0
ALT	4	0	0	0
Total bilirubin	3	1	1	0
GFR	3	2	0	0
Hypothyroidism	0	0	0	0

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GFR: Glomerular filtration rate.