Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 28, 2011; 17(12): 1519-1528
Published online Mar 28, 2011. doi: 10.3748/wjg.v17.i12.1519
Table 1 Main butyrate effects potentially useful in human medicine
Intestinal levelExtraintestinal level
Ion absorptionInsulin sensitivity
Cell proliferationCholesterol synthesis
Cell differentationEnergy expenditure
Intestinal barrier functionAmmonia scavenger
Immune-regulationStimulation of β-oxidation of very long chain fatty acids and peroxisome proliferation
Oxidative stressCFTR function
Intestinal motilityNeurogenesis
Visceral perception and rectal complianceHbF production