Copyright ©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 7, 2010; 16(41): 5181-5194
Published online Nov 7, 2010. doi: 10.3748/wjg.v16.i41.5181
Table 3 Cross-sectional studies on the association between Helicobacter pylori infection and growth retardation
Author (yr)/countryTotal No. of patients (H. pylori+)Age (range,yr)Diagnostic testConclusion
Perri et al[114] (1997)/Italy216 (49)3-14Urea breath testH. pylori infection was associated with growth delay, and poor socioeconomic status
Oderda et al[115] (1998)/Italy134 with short stature (27)5-13SerologyNo association with short stature
134 controls (18)5-13
Quiñonez et al[116] (1999)/Guatemala211 (107)5-10SerologyNo association with height for age and nutritional status
Choe et al[90] (2000)/Korea375 (63)10-15SerologyH. pylori infection accompanied by IDA, rather than H. pylori infection per se, was associated with delayed pubertal growth
Richter et al[117] (2001)/Germany3315 (213)5-7Urea breath testH. pylori infection was associated with growth delay
Ertem et al[118] (2002)/Turkey327 (162)3-12Urea breath testH. pylori infection was associated with short stature independently of poor living standards
Sood et al[119] (2005)/UK257 (97)-Urea breath testNo association with height and weight z scores, after adjustment for socioeconomic status and ethnicity
Süoglu et al[120] (2007)/Turkey70 (35)4-16EndoscopyH. pylori infection and IDA had a significant effect on height z scores, after adjustment for economic status
Mohammad et al[121] (2008)/Egypt286 (208)6-15Urea breath testH. pylori infection affected both body weight and height
Soylu et al[122] (2008)/Turkey108 with dyspepsia (57)7-17EndoscopyNo association with anthropometry. But, dyspeptic children had worse nutritional status compared to controls, regardless of H. pylori status
50 healthy controls8-17
Cherian et al[123] (2009)/Australia182 (149)< 16Stool antigenNo association with BMI or other anthropometric measures
Gulcan et al[124] (2010)/Turkey181 with RAP (121)6-15Endoscopy, 181RAP associated with gastric mucosal injury had a negative effect on BMI independent of H. pylori infection
309 asymptomatic (110)6-15Serology, 309RAP originating from H. pylori infection affected both BMI and linear growth