Up-regulation of PIK3CA promotes metastasis in gastric carcinoma

doi:10.3748/wjg.v16.i39.4986

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Oct 21, 2010 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2010; 16(39): 4986-4991
Published online Oct 21, 2010. doi: 10.3748/wjg.v16.i39.4986

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Figure 1 PIK3CA mRNA and protein expression in normal and gastric cancer tissues. A: Expression analyses of PIK3CA mRNA determined by real-time quantitative polymerase chain reaction, values are shown as mean ± SD; B: Immunohistochemical study of PIK3CA (original magnification: × 400). Negative or weak expression of PIK3CA in normal tissues around tumor; Positive expression of PIK3CA in primary gastric cancer tissues. Strong positive expression of PIK3CA was detected in lymph node metastasis and distant metastasis gastric cancer tissues. 1: Normal gastric mucosa; 2: Primary gastric cancer; 3: Lymph node metastasis in gastric cancer; 4: Distant metastasis in gastric cancer.

Citation: Liu JF, Zhou XK, Chen JH, Yi G, Chen HG, Ba MC, Lin SQ, Qi YC. Up-regulation of PIK3CA promotes metastasis in gastric carcinoma. World J Gastroenterol 2010; 16(39): 4986-4991
URL: https://www.wjgnet.com/1007-9327/full/v16/i39/4986.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i39.4986