Original Article
Copyright ©2010 Baishideng.
World J Gastroenterol. May 21, 2010; 16(19): 2362-2370
Published online May 21, 2010. doi: 10.3748/wjg.v16.i19.2362
Figure 3
Figure 3 Potentiation of cytotoxicity of gemcitabine by dicoumarol. KKU-100, KKU-OCA17, KKU-M214, and Chang liver cells were cultured in 96-well plates overnight. Cultured cells were pretreated with dicoumarol (0.1-10 μmol/L) for 4 h before treatment with gemcitabine at 1 nmol/L, 10 nmol/L, 1 nmol/L and 10 μmol/L, for KKU-100, KKU-OCA17, KKU-M214, and Chang liver cells, respectively. Antiproliferation was analyzed by staining the cells with fluorescent dyes before examination under fluorescent microscope. Bars represent mean ± SE, each from 3 experiments. aP < 0.05 vs control group.