Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure

Table 1 MARS treatment protocols for acute liver failure in Finland

Etiology	MARS treatment initiation criteria	Treatment protocol
Acute liver failure	Rapid deterioration of hepatic synthetic function and clinical condition despite conservative standard medical therapy	22-h sessions daily until:
	And one of the following criteria:	(1) Native liver recovers
	(1) Ingestion of a lethal dose of a known hepatotoxin (e.g. Amanita, paracetamol)	(2) Suitable transplant organ is found
	(2) The patient fulfills the criteria for highly urgent liver transplantation	(3) Irreversible multi-organ damage occurs

MARS: Molecular adsorbent recirculating system.