Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Mar 7, 2009; 15(9): 1025-1034
Published online Mar 7, 2009. doi: 10.3748/wjg.15.1025
Table 1 Clinical and biochemical characteristics of type 1 and type 2 autoimmune hepatitis
Type 1 AIHAnti-SMA, anti-ANA and/or anti-SLA
Mean age of onset: 10 yr old
Female:Male ratio 3:1
Higher incidence
Frequently associated with IBD and sclerosing cholangitis
Type 2 AIHAnti-LKM1 and/or anti-LC1
Mean age of onset: 6.5 yr old
Female:Male ratio 9:1
Associated with HLA DR3, DR7 and DQB1*0201
More severe disease
More likely to be resistant to treatment