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Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Dec 14, 2009; 15(46): 5770-5775
Published online Dec 14, 2009. doi: 10.3748/wjg.15.5770
Table 2 Confocal laser endomicroscopy (CLE) classification of Barrett’s esophagus
Confocal diagnosisVessel architectureCrypt architecture
Gastric-type epitheliumCapillaries with a regular shape only visible in the deeper parts of the mucosal layerRegular columnar-lined epithelium with round glandular openings and typical cobblestone appearance
Barrett’s epitheliumSubepithelial capillaries with a regular shape underneath columnar-lined epithelium visible in the upper and deeper parts of the mucosal layerColumnar-lined epithelium with intermittent dark mucin in goblet cells in the upper parts of the mucosal layer. In the deeper parts, villous, dark, regular cylindrical Barrett’s epithelial cells are present
NeoplasiaIrregular capillaries visible in the upper and deeper parts of the mucosal layer. Leakage of vessels leads to a heterogeneous and brighter signal intensity within the lamina propriaBlack cells with irregular apical and distal borders and shapes, with strong dark contrast against the surrounding tissue