Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. May 7, 2009; 15(17): 2125-2131
Published online May 7, 2009. doi: 10.3748/wjg.15.2125
Figure 2
Figure 2 The sensitivity of gastric smooth muscle to CNP. A, B: The row traces gastric smooth muscle spontaneous contractions in response to CNP in normal and diabetic rats; C-E: Summary of the contractility in response to CNP in normal and diabetic rats. CNP induced relaxation of gastric antral smooth muscle in control and diabetic rats (A, B). However, CNP-induced inhibition of spontaneous contraction was potentiated in diabetic rats, and the amplitude (C, n = 8, bP < 0.01) and frequency (D, n = 8, dP < 0.01) of spontaneous contraction were more potentially suppressed by CNP in diabetic rats. The inhibition time of CNP of spontaneous contraction was significantly prolonged in diabetic rats (E, n = 8, fP < 0.01).