Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. May 7, 2009; 15(17): 2097-2108
Published online May 7, 2009. doi: 10.3748/wjg.15.2097
Figure 6
Figure 6 FXR activation induces CSE gene expression and regulated CSE activity in the liver with cirrhosis. FXR +/+ and FXR -/- mice were treated with CCl4 and 6E-CDCA as described in the methods section. A and B: Quantitative real-time PCR of CSE mRNA and α1-collagen mRNA from FXR +/+ and FXR -/- liver homogenates; C: Liver CSE activity; D: Liver H2S production. Data are mean ± SD of six mice. aP < 0.05 versus FXR+/+ control mice. cP < 0.05 versus CCl4 FXR +/+ mice. eP < 0.05 versus FXR -/- control mice. gP < 0.05 versus CCl4 FXR -/- mice.