Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. May 7, 2009; 15(17): 2089-2096
Published online May 7, 2009. doi: 10.3748/wjg.15.2089
Figure 3
Figure 3 Impact of miR-196a on cellular signaling, in vitro chemosensitivity and in vivo induction of lung metastases. A: miR-196a transfection activates the AKT pathway but does not impact on the MEK pathway; B: miR-196a transfection significantly increases chemosensitivity towards oxaliplatin and cisplatin but not towards 5-FU or irinotecan; C: miR-196a significantly promoted growth of lung metastases in a xenograft biosystem after tail-vein injection and 7 wk of incubation.