Disruption of colonic barrier function and induction of mediator release by strains of Campylobacter jejuni that invade epithelial cells

Figure 2 Invasion of monolayers of HCA-7 cells determined by a gentamicin protection assay, corrected for the number of cells remaining per monolayer. C. jejuni strain 2801055 invaded the cells of the monolayer in a time-dependent manner, while strains 12189 and 2102011 showed no cellular invasion. Data are mean ± SE, n = 4. Analysis of variance showed that the total number of C. jejuni per monolayer was higher for those strains that abrogated transepithelial resistance compared to those that did not (P = 0.033), and that this increased with time (P = 0.02).