Viral Hepatitis
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jun 14, 2008; 14(22): 3490-3496
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3490
Figure 2
Figure 2 Construction of replicons of clinical HBV isolates using pHY106. Full-length HBV genomes from PCR amplication can be digested with Sap I and inserted into Sap I-digested pHY106 to produce HBV replicon. HBV open reading frames (ORFs) for the pre-core (PC), core, preS1 (PS1), preS2 (2) surface (S), polymerase, and X genes are indicated by square frame. Promoter sequences for the preS (PS), surface (S) and core (C) genes are indicated by arrows.