Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults

Table 3 Detection of individual probiotic genomic DNA from fecal samples by quantitative PCR at baseline and after the 3-wk probiotic intervention in healthy adults (n = 62)

Strain	Fecal samples
	Placebo (n = 16)		LGG (n = 13)		Bb12 (n = 16)		PJS (n = 17)
	Baseline	After intervention	Baseline	After intervention	Baseline	After intervention	Baseline	After intervention
L. rhamnosus GG
Number of subjects1	7	10	7	13	10	5	6	9
Mean (SD)2	4.7 (1.2)	5.1 (1.1)	5.1 (1.4)	8.6 (0.6)	5.2 (1.3)	4.6 (1.5)	4.5 (1.2)	5.0 (1.4)
B. animalis ssp. lactis Bb12
Number of subjects1	6	5	5	2	7	16	2	4
Mean (SD)2	5.4 (1.6)	5.3 (1.7)	5.3 (1.4)	4.9 (1.3)	5.4 (1.6)	8.6 (0.5)	4.7 (1.1)	5.1 (1.6)
P. freudenreichii ssp. shermanii JS
Number of subjects1	4	2	2	2	4	4	1	16
Mean (SD)2	4.5 (1.4)	4.0 (0.7)	4.1 (0.8)	4.0 (0.6)	4.4 (1.6)	4.2 (0.9)	3.8 (0.3)	8.3 (1.0)

¹Number of subjects harboring a detectable level of the strain.

²Mean (log₁₀) genome copies/g (SD). Detection limits for LGG and PJS is 3.7 log₁₀ genome copies/g and for Bb12 4.3 log₁₀ genome copies/g.