Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults

Table 1 Counts of cells of innate and adaptive immunity (10⁹/L) and levels of immunoglobulins (g/L) in serum and secretory IgA (g/mL) in saliva in healthy adults (n = 62) at baseline presented as median (IQR)

	Placebo (n = 16)	LGG (n = 13)	Bb12 (n = 16)	PJS (n = 17)	P value1
Leukocytes	4.90 (3.90-7.05)	5.20 (4.90-6.40)	5.25 (4.60-6.00)	4.90 (4.35 -5.70)	0.55
Monocytes	5.00 (4.25-6.75)	5.00 (5.00-6.00)	6.00 (5.00-6.00)	6.00 (4.50-6.50)	0.84
Neutrophils	2.05 (1.67-3.72)	3.10 (2.50-3.30)	2.95 (2.12-3.47)	3.10 (2.15-3.45)	0.39
Basophils	0.05 (0.00-0.10)	0.10 (0.00-0.10)	0.05 (0.00-0.10)	0.00 (0.00-0.10)	0.73
Eosinophils	4.00 (3.00-5.75)	3.00 (2.00-6.00)	3.00 (2.25-4.75)	2.00 (1.50-3.00)	0.077
Lymphocytes	38.0 (33.5-48.7)	35.0 (31.5-37.5)	34.0 (30.0-40.5)	31.0 (26.0-40.5)	0.24
IgM	1.28 (0.97-1.65)	0.87 (0.69-1.32)	1.10 (0.73-1.66)	1.44 (0.80-1.77)	0.31
IgG	10.7 (9.5-12.2)	10.3 (9.3-11.7)	10.6 (9.1-12.1)	10.4 (8.4-11.7)	0.72
IgA	2.65 (2.45-3.21)	2.42 (2.04-3.44)	2.20 (1.73-2.94)	2.44 (1.53-2.85)	0.22
sIgA	0.23 (0.15- 0.34)	0.27 (0.14-0.42)	0.40 (0.27-0.88)	0.28 (0.17-0.49)	0.065

¹Kruskall-Wallis test with Monte Carlo P values. IQR: Interquartile range.