Colorectal Cancer
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 28, 2006; 12(32): 5140-5147
Published online Aug 28, 2006. doi: 10.3748/wjg.v12.i32.5140
Figure 2
Figure 2 p-EGFR and p-KDR modulation after prolonged exposure to gefitinib or ZD6474. Cells were incubated with gefitinib or ZD6474 for 7 and 14 d with continuous and intermittent exposure. Drug-dependent modulation of p-EGFR (180 kDa) and p-KDR (195 kDa) was determined by immunoprecipitation followed by Western blotting. All data are shown relative to the baseline level (control = 0), which was similar after 7 and 14 d.