Colorectal Cancer
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. May 28, 2005; 11(20): 3040-3045
Published online May 28, 2005. doi: 10.3748/wjg.v11.i20.3040
Figure 6
Figure 6 Growth of COLO 205 tumor xenografts in nude mice was suppressed by denbinobin treatment. Athymic nude mice injected with COLO 205 cells into subcutaneous tissue of inter-scapular area. Once tumor volume reached approximately 200 mm3, the animal received treatment of 50 mg/kg denbinobin or DMSO intraperitoneally thrice per week for 4 wk. (A) Average tumor volume (B) body weight of DMSO-treated (n = 5, filled circles) vs denbinobin-treated (n = 4, open circles) nude mice. Samples were analyzed in each group, and values represent the mean±SE. Comparisons were subjected to linear regression method in (A) and showed significant difference between DMSO vs denbinobin treatment group.