Increased oxidative DNA damage, inducible nitric oxide synthase, nuclear factor κB expression and enhanced antiapoptosis-related proteins in Helicobacter pylori-infected non-cardiac gastric adenocarcinoma

Figure 1 Concentrations of 8-OHdG. A: Higher concentration of 8-OhdG in cancer tissues compared with adjacent non- cancer tissues. B: Higher concentration of 8-OhdG in cancer tissues of patients with and without H pylori infection. C: Significantly higher F8-OHdG concentrations in stage 3 and 4 patients ^aP < 0.05, N: non-cancer tissue, C: cancer tissue, Hp(-): without H pylori infection, Hp(+): with H pylori infection, 1&2: gastric cancer stages 1 and 2, 3&4: gastric cancer stages 3 and 4.