Downregulation of electroacupuncture at ST36 on TNF-α in rats with ulcerative colitis

Figure 1 Effect of EA on m_C/m_B. ^aP < 0.05, ^bP < 0.01 vs normal control; ^dP < 0.01, ^fP > 0.05 vs UC control; ^eP < 0.05 vs UC+EA at non-acupoint.

Figure 2 Colonic ultrastructure of UC control group: A, goblet cells, microvilli, endoplasmic reticula and mitochondria (TEM × 10000); B, inflammatory cells (TEM × 2500).

Figure 3 Colonic ultrastructure of UC+EA at ST36 group: A, goblet cells (TEM × 4000); B microvilli and mitochondria (TEM × 8000).

Figure 4 Colonic ultrastructure of EA+non-acupoint group: A, goblet cells, microvilli and mitochondria (TEM × 8000); B, endoplasmic reticula and mitochondria (TEM × 10000).

Figure 5 Effect of EA on colonic MPO activity. ^bP < 0.01 vs normal control; ^cP < 0.05, ^fP > 0.05 vs UC control; ^eP < 0.05 vs UC+EA at non-acupoint.

Figure 6 Effect of EA on TNF-α mRNA expression. A: Repre-sentative pictures of RT-PCR. Lane 1, 4, 7, 9: β-actin. Lane 2, 3, 6, 8: TNF-α. Lane 5, 10: DNA Marker (DL2000). B: Relative level of TNF-α mRNA expression. ^bP < 0.01 vs normal control; ^dP < 0.01, ^fP > 0.05 vs UC control; ^gP < 0.01 vs UC+EA at non-acupoint.

Figure 7 Effect of EA on serum TNF-α concentration. ^bP < 0.01 vs normal control; ^dP < 0.01, ^fP > 0.05 vs UC control; ^eP < 0.05 vs UC+EA at non-acupoint.