Investigation of Epstein-barr virus in Chinese colorectal tumors

Figure 1 Positive-control of LMP1 from lymphoma of Hodgkin’ disease. The cytoplasm of R-S cell showed clear positive signal.

Figure 2 immunohistochemical staining with anti-LMP1 antibody of adenoma specimen with dysplasia. The positive signals were localized at cytoplasm and membranes.

Figure 3 Immunohistochemical staining with anti-LMP1 antibody of colorectal carcinoma cells. The positive signals were localized at cytoplasm. But no clear positive signals localized at membranes.

Figure 4 Metastatic colorectal carcinoma cells in lymphatic. The cytoplasm of neoplasm cells showed LMP1 positive, the nucleic showed positive signals too.

Figure 5 The electrophoresis photo of PCR. Arrow points to the positive lane.

Figure 6 Positive control of EBER1 from a NPC specimen. Clear and strong hybridization signals (yellow nuclear grains) were shown in nuclei of the tumor cells. DAB and hematoxylin counterstaining, × 200.

Figure 7 In situ hybridization with EBER1 (from an carcinomatous adenoma). Positive signals were shown in nuclei of the tumor cells. DAB and hematoxylin counterstaining, × 200.

Figure 8 In situ hybridization with EBER1 (from a colorectal carcinoma). Clear and strong hybridization signals were shown in nuclei of the tumor cells. DAB and hematoxylin counterstaining, × 400

Figure 9 In situ hybridization with EBER1 (from a colorectal carcinoma, too). Interspersed positive signals were shown in neoplasm cells. DAB and hematoxylin counterstaining, × 400.