Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study

Figure 1 Definition of the γ-glutamyltransferase points and study design. The participants received one point if γ-glutamyltransferase (GGT) was in quartile 4 at each examination. The GGT points were defined as the sum of points of four examinations. GGT: Gamma-glutamyltransferase.

Figure 2 Incidence of site-specific digestive cancers according to the γ-glutamyltransferase points based on four consecutive examinations in men. GGT: Gamma-glutamyltransferase.

Figure 3 Subgroup analysis of the association of γ-glutamyltransferase points and the total digestive cancer incidence. A: Smoking (no smoking vs ever smoking); B: Alcohol consumption; C: Obesity (body mass index ≥ 25); D: Chronic hepatitis or liver cirrhosis in men. GGT: Gamma-glutamyltransferase; HR: hazard ratio.