Validation and evaluation of clinical prediction systems for first and repeated transarterial chemoembolization in unresectable hepatocellular carcinoma: A Chinese multicenter retrospective study

Figure 1 Flowchart of the patient selection process. HCC: Hepatocellular carcinoma; TACE: Transarterial chemoembolization.

Figure 2 Receiver operating characteristic curves for evaluating the radiological correlations of the scoring systems. A: Correlations between radiological response and predicting scores; B: Correlations between radiological response and risk stratifications based on the predictive systems for first transarterial chemoembolization. HAP: Hepatoma Arterial-embolization Prognostic; mHAP: Modified HAP; 6&12: Six-and-twelve criteria.

Figure 3 Time-dependent receiver operating characteristic curves for comparisons. A: Comparisons among prognostic systems in first transarterial chemoembolization; B: Comparisons among prognostic systems in repeated transarterial chemoembolization. AUROC: Area under receiver operating characteristic curve; HAP: Hepatoma Arterial-embolization Prognostic; mHAP: Modified HAP; 6&12: Six-and-twelve criteria; ART: Assessment for re-treatment with TACE; ABCR: Alpha-fetoprotein, BCLC stage, Child-Pugh and Response.

Figure 4 Survival curves between candidates and non-candidates according to sequential use of the Hepatoma Arterial-embolization Prognostic system version 3 and alpha-fetoprotein, BCLC stage, Child-Pugh and Response system. re-TACE: Repeated transarterial chemoembolization.