Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma

Figure 1 Flowchart indicating the method of patient enrollment. HCC: Hepatocellular carcinoma; RFA: Radiofrequency ablation.

Figure 2 Recurrence curves of 661 patients with hepatocellular carcinoma treated with radiofrequency ablation. A: Cumulative rates of recurrence. The 1-, 3-, 5-, 8-, and 10-year cumulative rates of recurrence were 15.1%, 43.8%, 62.5%, 77.9%, and 92.7%, respectively; B: Cumulative rates of extrahepatic metastasis. The 1-, 3-, 5-, 8-, and 10-year cumulative rates of extrahepatic metastasis were 1.0%, 2.9%, 8.1%, 15.7%, and 33.7%, respectively.

Figure 3 Timelines of recurrence of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma. RFA: Radiofrequency ablation; EHM: Extrahepatic metastasis; RFS: Recurrence-free survival.

Figure 4 Cumulative occurrence of extrahepatic metastasis in patients with recurrence of hepatocellular carcinoma after radiofrequency ablation: Stratified by numbers of risk factors.