Opinion Review
Copyright ©The Author(s) 2020.
World J Gastroenterol. May 14, 2020; 26(18): 2126-2137
Published online May 14, 2020. doi: 10.3748/wjg.v26.i18.2126
Figure 1
Figure 1 Involvement of Annexin A2 in the change of immune microenvironment. A: The expression of ANXA2 mRNA according to The Cancer Genome Atlas database; B: Increased ANXA2 results in poorer 5-year overall survival; C: The proportion of 22 infiltrating immune cells; D: Gene ontology analysis of differentially expressed genes. ANXA2: Annexin A2; HCC: Hepatocellular carcinoma.
Figure 2
Figure 2 Increased Annexin A2 promotes immune escape in hepatocellular carcinoma patients. A: Correlation of partial labeled genes of regulatory T cells; B: Correlation of partial labeled genes of activated natural killer cells; C: Correlation of partial labeled genes of activated dendritic cells; D: The expression of partial checkpoint molecules; E: The expression of partial inhibitory molecules and effector molecules. ANXA2: Annexin A2; NK: Natural killer.