Hereditary gastric cancer: Three rules to reduce missed diagnoses

doi:10.3748/wjg.v26.i13.1382

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2020; 26(13): 1382-1393
Published online Apr 7, 2020. doi: 10.3748/wjg.v26.i13.1382

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Figure 1 Diagnosis criteria for hereditary gastric cancer caught by rule number 1. GC: Gastric cancer; FIGC: Familial intestinal gastric cancer; GAPPS: Gastric adenocarcinoma and proximal polyposis of stomach; HDGC: Hereditary diffuse gastric cancer.

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Figure 2 Diagnosis criteria for hereditary gastric cancer caught by rule number 2. GC: Gastric cancer; FIGC: Familial intestinal gastric cancer; GAPPS: Gastric adenocarcinoma and proximal polyposis of stomach; HDGC: Hereditary diffuse gastric cancer.

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Figure 3 Diagnosis criteria for hereditary gastric cancer caught by rule number 3. GC: Gastric cancer; FIGC: Familial intestinal gastric cancer; GAPPS: Gastric adenocarcinoma and proximal polyposis of stomach; HDGC: Hereditary diffuse gastric cancer.

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Figure 4 The three-rules strategy, comprising every current clinical criterion. GC: Gastric cancer; FIGC: Familial intestinal gastric cancer; GAPPS: Gastric adenocarcinoma and proximal polyposis of stomach; HDGC: Hereditary diffuse gastric cancer.

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Figure 5 How to diagnose and manage hereditary diffuse gastric cancer by applying rule number 1. The first numbers in white squares refer to early-onset (under 50 years old) cases, and the second numbers refer to the quantity of affected relatives. GC: Gastric cancer; HGC: Hereditary gastric cancer.

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Figure 6 Clinical management of hereditary diffuse gastric cancer syndrome.

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Figure 7 How to diagnose and manage familial intestinal gastric cancer by applying rule number 1. GC: Gastric cancer; HGC: Hereditary gastric cancer.

Citation: Assumpção P, Araújo T, Khayat A, Ishak G, Santos S, Barra W, Acioli JF, Rossi B, Assumpção P. Hereditary gastric cancer: Three rules to reduce missed diagnoses. World J Gastroenterol 2020; 26(13): 1382-1393
URL: https://www.wjgnet.com/1007-9327/full/v26/i13/1382.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i13.1382