Examining pathogenic concepts of autoimmune hepatitis for cues to future investigations and interventions

Figure 1 Pathogenic mechanisms implicated in autoimmune hepatitis. The components of each putative mechanism are shown under each panel. MHC: Major histocompatibility complex; TCR: T cell antigen receptor; PD-1: Programmed cell death protein-1.

Figure 2 Pathogenic mechanisms and factors associated with susceptibility, onset, and maintenance of autoimmune hepatitis and possible therapeutic interventions. Pathogenic mechanisms and factors are shown, and possible therapeutic interventions for each aspect of the disease are indicated alongside the arrows. PD-1: Programmed cell death protein-1.