Case Report
Copyright ©The Author(s) 2018.
World J Gastroenterol. May 7, 2018; 24(17): 1919-1924
Published online May 7, 2018. doi: 10.3748/wjg.v24.i17.1919
Figure 1
Figure 1 Full sequencing analysis of the hepatitis B virus reverse transcriptase gene from the patient (Korean sample). The sequence analysis shows that mutations occurred at 9 sites compared to the wild-type genotype C (the patient was infected with genotype C). The rt106 and rt118 sites are expressed as “?” because the sites contained a substitution by 2 different nucleotides.
Figure 2
Figure 2 Chromatogram of the hepatitis B virus reverse transcriptase gene from the patient. The rt101 (red arrow) and rt118 (arrow) sites are shown as a double line because the site contained a substitution by 2 different nucleotides (cytosine and guanine).
Figure 3
Figure 3 Clinical course of the patient. Hepatitis B virus DNA became undetectable after 16 mo of antiviral treatment with TDF. Virologic and biochemical breakthroughs occurred at 43 mo after treatment initiation.