CDX2 protein expression compared to alcian blue staining in the evaluation of esophageal intestinal metaplasia

Figure 1 An example of Barrett mucosa showing numerous goblet cells (A) which are positive for alcian blue pH 2. 5 stain (B) and CDX2 (C). Magnification × 200.

Figure 2 Biopsy showing glands with columnar blue cells on the alcian blue pH 2. 5 staining (A) while the same cells are negative when stained with CDX2 (B). Magnification × 200.

Figure 3 Image of esophageal glands with associated esophageal gland ducts (A) strongly positive for alcian blue pH 2. 5 staining (B) but are negative for CDX2 (C). Magnification × 200.

Figure 4 Esophago-gastric mucosa showing negativity for intestinal metaplasia on the alcian blue pH 2. 5 staining (A), but strong positivity on the CDX2 immunostain (B). Magnification × 200.