Copyright ©The Author(s) 2015.
World J Gastroenterol. Nov 14, 2015; 21(42): 12150-12156
Published online Nov 14, 2015. doi: 10.3748/wjg.v21.i42.12150
Figure 1
Figure 1 Outline of the overall aspects of this review. The subcellular localization of p21 and other tumor suppressors is regulated by CRM1. Inhibition of CRM1 by specific inhibitors and IFN may play a role in future anti-hepatocellular carcinoma strategies. CRM1: Chromosome region maintenance 1; IFN: Interferon; SINE: Selective inhibitors of nuclear export.